HocusLocus is developing a novel method for cell line selection we call PTSelect™. In short, PTSelect™ combines three currently used technologies, RNAi/siRNAs, mRNA transfection, and magnetic and/or fluorescence activated cell sorting, into a powerful, robust and flexible method for cell line selection. This paradigm-shifting technique offers the potential for fast, high quality pools that provide clones with higher titers. PTSelect can select against each protein component individually in complex molecules and perform the selection to produce clones with the desired ratio between components. Also, the flexibility of the system allows for quick testing and evaluation of selection progress.
Use the contact form if you are interested in evaluating the PTSelect protocol.